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Program

9:00-9:30 Registration

9:30-9:40Welcome and Introduction

9:40-11:00 Oral Session 1

9:40 – Ilaria Gentile, Biagio Cangiano “Pathogenic TBX3 variants interfere with GnRH neuron development: evidence from CHH patients and functional models

10:00 – Matteo Brizioli “Surface of biomolecular condensates: a distorted mirror reflecting their material properties

10:15 – Marika Viatore “Occurrence and biology of multinucleated giant macrophages in human PDAC

10:30 – (Invited speaker) Michela DeleidiExploring human susceptibility to Parkinson’s disease in brain organoids”

11:00-11:30 Coffee break

11:30 12:45Oral Session 2

11:30 – Clara De Palma, Sara Grassi (PSR talk) “Role of ganglioside GM3 in myoblasts’ differentiation

11:50 – Gianluigi Marco Aldo Oggionni “Autonomic Nervous System Control In Male And Female Elite Soccer Players: Importance Of Different Training Routines And Perceived Stress

12:05 – Simone Codispoti “RNA-Peptide World: prebiotic peptides & libraries driving ancestral ribosome coacervation

12:20 – Arteda Paplekaj “Molecular peace under pressure: LSD1 splicing and ESR1 modulation define stress resilience

12:35-12:50 Flash talks

12:50BIOMETRA Group-Portrait

13:00-15:00Lunch & Poster session

15:00-15:45Oral Session 3

15:00 – Sabrina Carbone, Gaia Galassi “Towards more effective Glioblastoma Multiforme therapies: HDAC6 and HDAC8 combined targeting

15:20 – Guillaume Gilliard “Role of protein microenvironment in the interaction of breast cancer cell extracellular vesicles with lipid membranes

15:35 – Ottavia Maria Roggero “Role of IL-6 in Rett syndrome: from in vitro findings to in vivo therapeutic target validation

15:50 – Filippo Chiesa “Leveraging Brain Organoids to Explore Congenital Central Hypoventilation Syndrome (CCHS)

16:05-17:15BIOMETRA Games Team building activities

17:15-18:30Awardsand Final Remarks, Aperitif

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